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Inherited disorders are a serious threat for those countries which are situated on consanguinity belt. Pakistan, a country consists of Punjab, Khyber Pakhtoonkhwa, Balochistan, Sindh, Gilgat Baltistan, FATA and a State of Azad Jammu & Kashmir, has 62.7% consanguineous rate. Marriages among close clan are a traditionally implemented process in this ethnic group. Thus high inbreeding rate increases the frequency of disease allele and leads to high mortality rate due to genetic disorders.Genetic disorders are classified into chromosomal aberration, Single Gene Disorders Mitochondrial conditions.........

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  • Kohat University of Science & Technology , Pakistan
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  • pakgmd@gmail.com
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